Targeting cancer's weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model
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چکیده
منابع مشابه
Targeting cancer's weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model.
In the atavistic model of cancer progression, tumor cell dedifferentiation is interpreted as a reversion to phylogenetically earlier capabilities. The more recently evolved capabilities are compromised first during cancer progression. This suggests a therapeutic strategy for targeting cancer: design challenges to cancer that can only be met by the recently evolved capabilities no longer functio...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2014
ISSN: 0265-9247
DOI: 10.1002/bies.201400070